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ADVANCES IN LIPID RESEARCH Vol. 11

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This volume of Advances in Lipid Research contains discussions of a wide range of topics, all of which are part of the broad lipid field. The first review concerns itself with a serum enzyme whose action had
been described over 35 years ago but whose characterization is more recent. This enzyme is lecithin: cholesterol acyltransferase, or LCAT. The article reviews the metabolic role of this enzyme. The second chapter covers a topic which is becoming increasingly important in metabolic and clinical research, namely, simple means of separation and quanti- tation of serum lipoproteins. This chapter offers a guide to the many variations of the reaction involving lipoproteins, divalent cations, and polyanionic substances, organic and inorganic. It systematizes the current knowledge. In the third article the metabolism of fatty acids by brain tissue is reviewed. The concept of the blood-brain barrier is discussed critically and its role in fatty acid uptake is assessed. As our knowledge of the metabolic role of bile acids deepens, it becomes increasingly evident that the production or excretion of these steroids may be im- portant in the establishment of cholesteremia, lithogenesis, and possibly cancer. Many of the alterations in bile acid structure are due to their interaction with the intestinal microflora, and this relationship is the basis of the fourth review. The plant sterols may play more than a simple structural role. As research reveals the multiple aspects of plant sterol function it becomes important for us to have a better understanding of their chemistry and metabolism. The fifth chapter provides such a review of the phytosterols. For normal metabolism insects require an exogenous source of sterol, being incapable of sterol synthesis. Insects can utilize and metabolize dietary sterol, and how this is accomplished is reviewed in the sixth chapter. The last chapter covers a field which has intrigued biologists for decades-the lipids of viruses. The elucidation of the role lipids play in viral structure and metabolism has had to wait for the development of sophisticated methodology. Now that we have the ana- lytical tools, this entire area will open up. As this chapter shows, ubiquitous lipid is important even in the smallest of integrated biological units

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Availability

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547.915.95:577.1(058) PAO a

Perpustakaan PPKS Medan Lt. 1 (547.915.95:577.1(058))

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Detail Information

Series Title

11

Call Number

547.915.95:577.1(058) PAO a

Publisher

New York : Academic Press., 1973

Collation

vii, 363 hal.;ill 23,5 cm

Language

English

ISBN/ISSN

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Classification

547.915.95:577.1(058)

Content Type

-

Media Type

-

Carrier Type

-

Edition

11

Subject(s)

Research

Specific Detail Info

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Statement of Responsibility

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