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ADVANCES IN LIPID RESEARCH Vol. 9

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The topics in this volume of Advances in Lipid Research, which range from sophisticated methodology to steroid chemistry, again attest to the breadth of the field of lipid chemistry. The first article is an exposition of a technologically difficult but

ncreasingly important aspect of autoradiography; namely, the coupling of this technique with light and electron microscopic analy- sis. With the proliferating use of electron microscopy, the techniques discussed in this paper permit its wider adaptation to the study of the finer points of lipid absorption and transport. The area of fatty acid biosynthesis is reexamined from a new standpoint in the second chapter. The question of carbon source in the biosynthesis of fatty acids has been the subject of numerous reviews but here the source(s) of the hydrogen atoms are reviewed. The third article is also con- cerned with fatty acid biosynthesis but in a special tissue, the aorta. It is increasingly evident that aortic lipid metabolism is an important factor in the development of atherosclerosis. The aorta has been shown to synthesize an appreciable amount of fatty acid but little sterol; the third chapter contains an in-depth discussion of factors affecting fatty acid synthesis by aortic tissue. Another currently im- portant aspect of lipid chemistry is the role of lipids in membranes. Membrane structure and chemistry are of importance in all areas of biology. Since lipids are central to membrane structure, these topics are of general biological importance. The fourth paper contains a discussion of membrane structure and the lipids of membranes. The fifth chapter covers the subject of glycosphingolipids. These complex lipids play an integral role in the structure of nervous tissue, and defects in their synthesis or metabolism may lead to various neuro- logic disorders. The material in this chapter permits a broader under- standing of these compounds. The sixth article stretches the definition of lipid chemistry to include pregnane derivatives. Actually, these compounds qualify by the operational definition that lipids are com- pounds soluble in lipid solvents. This chapter will afford the reader an insight into the chemistry and biochemistry of the Ca, steroids. The last paper provides a complete review of the composition of vegetable oils. There is continuing interest in vegetable oils in diet formulation and other aspects of fat metabolism, especially as related to cholesterol metabolism. This article contains important ancillary information for anyone engaged in such research

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547.915.95:577.1(058) PAO a

Perpustakaan PPKS Medan Lt. 1 (547.915.95:577.1(058))

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Series Title

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Call Number

547.915.95:577.1(058) PAO a

Publisher

New York : Academic Press., 1971

Collation

xxvii, 418 hal.: ill.;23,5cm

Language

English

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Classification

547.915.95:577.1(058)

Content Type

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Media Type

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Carrier Type

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Edition

9

Subject(s)

Research

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