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ANNUAL REVIEW OF BIOCHEMISTRY Vol. I
It is not without significance that the last few years have witnessed the inception of new journals, of interest to chemists, at no less a rate than one every two weeks. The periodical literature of other sciences has swollen likewise. New journals have been established and the existing ones expanded. Most of us find ourselves buried amidst piles of unread papers. To keep abreast of the literature in biochemistry has become a Herculean task. It is the exceptional individual who succeeds in reading an appreciable proportion of the papers outside the confines of his own restricted field of research.
The recognition of such a situation would seem to call for apolo- gies and explanations from any who would venture to introduce still another publication. We hope, however, that the Review will be of material assistance; for it is in the belief that critical surveys of the literature will minimize the task of constantly referring to original works that the Annual Review of Biochemistry will present from year to year reviews of the current developments in from twenty-five to thirty of the major fields of interest. It is expected that these syste- matic surveys of the literature will supplement the valuable service already given by existing reviews in closely related fields.
Doubtless, all readers of the Review will appreciate the difficulties with which the reviewers have been confronted in the selection of papers for consideration. Although it has been intended that the re- views shall be as comprehensive as possible, severe restrictions have been imposed by the space available. It became necessary for the re- viewers either to omit many papers from treatment or to prepare a mere compendium of the literature. Guided by the principle that critical analyses and résumés would be of greater value, attention has been centered, in most instances, upon selected aspects of the particu- lar topic under review, and every effort has been made to discuss, as adequately as space permitted, the most significant contributions to the subject. In consequence, other fields of majorinterest, even though embraced by one or another of the topics contained in the vol- ume, have been deliberately omitted for the present. It is fully ex- pected that such omissions will be remedied by adequate consideration in future volumes, in which such topics may simply alternate from year to year with some of those now receiving treatment. Despite every effort to keep the volume of moderate size, it has
far outgrown our original expectations. This expansion has been due to the need of developing historical backgrounds in certain of the reviews and to unexpectedly numerous items requiring mention, Vol. ume II, which will appear in the spring of 1933, will closely approach the standard size of 400 pages intended for the Review.
encouragement, advice, Acknowledgment must be made of the mated and received from colleagues in this material aid merit may be attached to the Review is due, in large pad, W the judgment and experience of the many from whom advice art, solicited.
liciteresponse to a widely circulated request, many have been good enough to send reprints of recent publications to the reviewers. Sood of these pertained to topics beyond the scope of the Review, but others were of the greatest convenience and aid. Where the journal of origi nal publication was inaccessible, the use of reprints became especially urgent. The courteous co-operation of all who have joined in supply- ing reprints is most gratefully acknowledged.
We are especially indebted to Mr. Francis Garvan and the Chemi- cal Foundation for a generous subsidy covering the first three years of the Review, and to Dr. Richard J. Block for additional financial aid. Without such support, the Review could not have been established.
To Stanford University our thanks are due for encouragement, cordial endorsement of the enterprise, and substantial assistance dur- ing months of organization. The Stanford University Press has given to the Review its enthusiastic support and has labored patiently and carefully over the editing, the composition, and the final preparation of the volume.
Every attempt has been made by all associated with the Review to produce an excellent and useful work. Nevertheless, the enterprise is young and its deficiencies are manifold. It will be a satisfaction to thereviewers, the advisory committee, and the Press if readers will suggest freely the ways in which improvement may be made
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